Abstract
A recent report describes the identification through the use of in vitro selection of a peptide that antagonizes Methuselah signaling in Drosophila in vitro and extends fly life span in vivo.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Drosophila Proteins / antagonists & inhibitors*
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Drosophila Proteins / chemistry
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Drosophila melanogaster / physiology*
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Drug Design*
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Ligands
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Longevity / drug effects*
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Oligopeptides / pharmacology*
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Protein Conformation
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Receptors, G-Protein-Coupled / antagonists & inhibitors*
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Receptors, G-Protein-Coupled / chemistry
Substances
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Drosophila Proteins
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Ligands
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Oligopeptides
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Receptors, G-Protein-Coupled
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arginyl-tryptophyl-arginine
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mth protein, Drosophila