Non-specific amplification of patient-specific Ig/TCR gene rearrangements depends on the time point during therapy: implications for minimal residual disease monitoring

MeSH terms

• Bone Marrow Cells / chemistry
• Bone Marrow Cells / pathology
• DNA, Neoplasm / analysis
• DNA, Neoplasm / genetics*
• False Positive Reactions
• Gene Rearrangement, B-Lymphocyte*
• Gene Rearrangement, T-Lymphocyte*
• Humans
• Neoplasm, Residual
• Polymerase Chain Reaction / methods*
• Practice Guidelines as Topic
• Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
• Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology*
• Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
• Time Factors