Reactions of Cp2MCl2 (M=Ti or Zr) with imine-oxime ligands. Formation of metallacycles

Molecules. 2005 Jul 14;10(6):653-8. doi: 10.3390/10060653.

Abstract

The reactions of bis(cyclopentadienyl)titanium(IV)/zirconium(IV) dichloride with a series of imine-oxime ligands (LH2), derived by condensing benzil-alpha-monoxime and 2-phenylenediamine, 4-phenylenediamine, 4-methyl-2-phenylenediamine, 2,6-diamino-pyridine, have been studied in anhydrous tetrahydrofuran in the presence of base and metallocycles of the [Cp2M(L)] (M=Ti or Zr) type have been isolated. Tentative structures have been proposed for the products based on elemental analysis, electrical conductance and spectral (electronic, IR and (1)H-NMR) data. Proton NMR spectra indicate that on the NMR time scale there is rapid rotation of the cyclopentadienyl ring around the metal-ring axis at 25 degrees C. Studies were conducted to assess the growth inhibiting potential of the complexes synthesized and the ligands against various bacterial strains.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / pharmacology
  • Cyclization
  • Imines / chemistry*
  • Ligands
  • Molecular Structure
  • Organometallic Compounds / chemistry*
  • Oximes / chemistry*
  • Spectrum Analysis
  • Titanium / chemistry
  • Zirconium / chemistry

Substances

  • Anti-Bacterial Agents
  • Imines
  • Ligands
  • Organometallic Compounds
  • Oximes
  • Zirconium
  • Titanium