Major depressive disorder

N Engl J Med. 2008 Jan 3;358(1):55-68. doi: 10.1056/NEJMra073096.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Antidepressive Agents / pharmacology
  • Biogenic Monoamines / physiology*
  • Corticotropin-Releasing Hormone / physiology
  • Depressive Disorder, Major / etiology*
  • Depressive Disorder, Major / genetics
  • Depressive Disorder, Major / physiopathology
  • Humans
  • Hydrocortisone / blood
  • Hydrocortisone / physiology*
  • Hypothalamo-Hypophyseal System / physiology
  • Norepinephrine / metabolism
  • Pituitary-Adrenal System / physiology
  • Serotonin / metabolism
  • Stress, Psychological / complications
  • Stress, Psychological / physiopathology

Substances

  • Antidepressive Agents
  • Biogenic Monoamines
  • Serotonin
  • Corticotropin-Releasing Hormone
  • Hydrocortisone
  • Norepinephrine