The effect of dietary phosphorus and calcium level, phytase supplementation, and ileal infusion of pectin on the chemical composition and carbohydrase activity of fecal bacteria and the level of microbial metabolites in the gastrointestinal tract of pigs

J Anim Sci. 2008 Jul;86(7):1544-55. doi: 10.2527/jas.2007-0267. Epub 2008 Mar 14.

Abstract

Two experiments with growing pigs were conducted to determine the effects of dietary P and Ca level, phytase supplementation, and ileal pectin infusion on ileal and fecal P and Ca balance, chemical composition of fecal mixed bacterial mass (MBM), and bacterial metabolic activity. Pigs (initial BW = 30 kg) were fitted with simple T-cannulas at the distal ileum. They were fed a low-P corn-soybean meal control diet (3 g of P/kg) or the control diet supplemented with monocalcium phosphate (MCP; 7 g of P/kg; Exp. 1) or 1,000 FTU phytase/kg (Exp. 2). The daily infusion treatments consisted of 60 g of pectin dissolved in 1.8 L of demineralized water or 1.8 L of demineralized water as the control infusion, infused via the ileal cannula. In each experiment, 8 barrows were assigned to 4 dietary treatments according to a double, incomplete 4 x 2 Latin square. The dietary treatments in Exp. 1 were the control (Con-) diet with water infusion; the control (Con+) diet with pectin infusion; the MCP diet with water infusion; and the MCP diet with pectin infusion. In Exp. 2, the pigs received the same Con- and Con+ treatments as in Exp. 1 and, in addition, the phytase-supplemented diet in combination with water or pectin infusion. After a 15-d adaptation period, feces were collected for 5 d followed by ileal digesta collection for 24 h. In Exp. 1, supplemental MCP increased (P </= 0.003) ileal and fecal P and Ca recovery as well as P and Ca content of the MBM. Pectin infusion increased the N content of the MBM (P = 0.054) and polygalacturonase activity (P = 0.032) in feces. In addition, pectin decreased (P = 0.049) ileal and tended (P < 0. 079) to increase fecal VFA concentrations. In Exp. 2, phytase decreased ileal and fecal P recovery (P < 0.001) and the P content of the MBM (P = 0.045), whereas the N content of the MBM (P = 0.094) and fecal cellulase activity (P = 0.089) tended to decrease. Similarly, pectin infusion decreased (P = 0.036) fecal cellulase activity but increased (P < 0.001) polygalacturonase activity. In conclusion, these data indicate that bacterial P and Ca assimilation and metabolic activity depend on P and Ca availability in the large intestine and on the availability of fermentable substrate, such as pectin. Thus, increasing dietary P and Ca levels increases bacterial P and Ca assimilation due to greater intestinal P and Ca availability, whereas decreasing intestinal P availability for bacteria through phytase addition to low-P diets reduces bacterial P incorporation and seems to decrease bacterial activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 6-Phytase / administration & dosage*
  • 6-Phytase / metabolism
  • Amino Acids / metabolism
  • Amylases / metabolism
  • Animal Nutritional Physiological Phenomena / physiology
  • Animals
  • Bacteria / enzymology*
  • Calcium Phosphates / administration & dosage
  • Calcium Phosphates / metabolism
  • Calcium, Dietary / administration & dosage*
  • Calcium, Dietary / metabolism
  • Cellulase / metabolism
  • Feces / chemistry
  • Feces / microbiology
  • Gastrointestinal Tract / drug effects
  • Gastrointestinal Tract / metabolism
  • Gastrointestinal Tract / microbiology*
  • Glycoside Hydrolases / metabolism*
  • Ilium / drug effects
  • Ilium / metabolism
  • Ilium / microbiology
  • Male
  • Pectins / administration & dosage*
  • Phosphorus, Dietary / administration & dosage*
  • Phosphorus, Dietary / metabolism
  • Polygalacturonase / metabolism
  • Random Allocation
  • Swine / metabolism*
  • Swine / microbiology

Substances

  • Amino Acids
  • Calcium Phosphates
  • Calcium, Dietary
  • Phosphorus, Dietary
  • calcium phosphate, monobasic, anhydrous
  • Pectins
  • 6-Phytase
  • Amylases
  • Glycoside Hydrolases
  • carbohydrase
  • Polygalacturonase
  • Cellulase