Enzymatic properties of the neuraminidase of seasonal H1N1 influenza viruses provide insights for the emergence of natural resistance to oseltamivir

PLoS Pathog. 2008 Jul 25;4(7):e1000103. doi: 10.1371/journal.ppat.1000103.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antiviral Agents / pharmacology*
  • Base Sequence
  • Cytokines
  • DNA, Viral / analysis
  • Drug Resistance, Viral / drug effects*
  • Drug Resistance, Viral / physiology
  • Enzyme Inhibitors / pharmacology*
  • Influenza A Virus, H1N1 Subtype / drug effects
  • Influenza A Virus, H1N1 Subtype / enzymology*
  • Microbial Sensitivity Tests
  • Molecular Sequence Data
  • Neuraminidase / antagonists & inhibitors*
  • Oseltamivir / pharmacology*
  • Phylogeny
  • Seasons
  • Tumor Suppressor Proteins
  • Virus Replication / physiology

Substances

  • Antiviral Agents
  • Cytokines
  • DNA, Viral
  • Enzyme Inhibitors
  • SCGB3A1 protein, human
  • Tumor Suppressor Proteins
  • Oseltamivir
  • Neuraminidase