[Ovarian epithelial dysplasia: myth or reality? Review]

Gynecol Obstet Fertil. 2008 Jul-Aug;36(7-8):800-7. doi: 10.1016/j.gyobfe.2008.05.003. Epub 2008 Jul 25.
[Article in French]

Abstract

Ovarian epithelial dysplasia has been described in the ovarian surface epithelium by histologic, morphometric and nuclear profile studies. It could represent a potential precursor of ovarian malignancy in patients with genetic risk of ovarian cancer, although its natural history and progression to carcinoma are unpredictable. Diagnosis and identification of ovarian dysplasia would certainly be useful to understand the early steps of ovarian carcinogenesis. However, dysplasia in relation with ovulation induction seems to have a different pattern. We report dysplasia definitions and the current clinical management.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Female
  • Genes, BRCA1
  • Genes, BRCA2
  • Humans
  • Immunohistochemistry
  • Ovarian Diseases / classification
  • Ovarian Diseases / complications
  • Ovarian Diseases / pathology*
  • Ovarian Neoplasms / epidemiology
  • Ovarian Neoplasms / genetics
  • Ovulation
  • Uterine Cervical Dysplasia / classification
  • Uterine Cervical Dysplasia / complications
  • Uterine Cervical Dysplasia / pathology*