Gene regulation: a tale of germline mRNA tails

Curr Biol. 2008 Oct 14;18(19):R915-6. doi: 10.1016/j.cub.2008.08.001.

Abstract

Gene regulation often plays by different rules in the germline compared to the soma. In Caenorhabditis elegans, the spatial and temporal expression of germline genes is controlled post-transcriptionally via the 3' UTR rather than transcriptionally via the promoter.

Publication types

  • Kommentar

MeSH terms

  • 3' Untranslated Regions / metabolism*
  • Animals
  • Caenorhabditis elegans
  • Gene Expression Regulation, Developmental
  • Germ Cells / metabolism*
  • RNA Processing, Post-Transcriptional*
  • RNA, Messenger / metabolism*

Substances

  • 3' Untranslated Regions
  • RNA, Messenger