Crossing the rubicon

Nat Biotechnol. 2009 Jan;27(1):42-4. doi: 10.1038/nbt0109-42.

Abstract

A viral vector injected intravenously in mice crosses the blood-brain barrier and transduces widespread regions of the brain and spinal cord.

Publication types

  • Kommentar
  • News

MeSH terms

  • Animals
  • Blood-Brain Barrier
  • Brain / drug effects*
  • Dependovirus / metabolism
  • Gene Transfer Techniques
  • Genetic Techniques
  • Genetic Vectors*
  • Humans
  • Inflammation
  • Ions
  • Mice
  • Models, Biological
  • Spinal Cord / drug effects*

Substances

  • Ions