Exogenous re-infection by a novel Streptococcus pneumoniae serotype 14 as a cause of recurrent meningitis in a child from The Gambia

Martin Antonio; Claire Oluwalana; Ousman Secka; Tumani Corrah; Stephen Howie; Richard A Adegbola

doi:10.1186/1476-0711-8-3

Exogenous re-infection by a novel Streptococcus pneumoniae serotype 14 as a cause of recurrent meningitis in a child from The Gambia

Ann Clin Microbiol Antimicrob. 2009 Jan 20:8:3. doi: 10.1186/1476-0711-8-3.

Authors

Martin Antonio¹, Claire Oluwalana, Ousman Secka, Tumani Corrah, Stephen Howie, Richard A Adegbola

Affiliation

¹ Bacterial Diseases Programme, Medical Research Council Laboratories, Banjul, The Gambia, Africa. [email protected]

Abstract

We report a case of an infant who experienced exogenous re-infection of Streptococcus pneumoniae serotype 14 as a cause of recurrent meningitis after apparently successful antibiotic treatment with ceftriaxone. eBURST analysis revealed that isolates from the two episodes of meningitis belonged to hypervirulent ST63 and ST3321 clonal complexes respectively.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Bacterial Typing Techniques
Female
Gambia
Humans
Infant
Meningitis, Pneumococcal / microbiology*
Meningitis, Pneumococcal / prevention & control
Recurrence
Sequence Analysis, DNA*
Serotyping
Streptococcus pneumoniae / classification*
Streptococcus pneumoniae / genetics
Streptococcus pneumoniae / isolation & purification*
Streptococcus pneumoniae / pathogenicity

Abstract

Publication types

MeSH terms

Grants and funding