Abstract
Two new mexicanolide-type limonoids, named xylomexicanin A (1) and xylomexicanin B (2), were isolated from seeds of the Chinese mangrove Xylocarpus granatum. Their structures were elucidated on the basis of spectroscopic methods. Compound 1 exhibited antiproliferative activity against human breast carcinoma cells (KT), while 2 did not show inhibitory effects on eleven human tumour cell lines tested.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents / chemistry*
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Antineoplastic Agents / isolation & purification
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Antineoplastic Agents / pharmacology*
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Asia, Southeastern
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Breast Neoplasms / drug therapy*
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Cell Line, Tumor / drug effects
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Female
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Humans
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Limonins / chemistry*
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Limonins / isolation & purification
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Limonins / pharmacology*
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Magnetic Resonance Spectroscopy
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Medicine, Traditional
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Meliaceae / chemistry*
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Neoplasms / drug therapy*
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Seeds / chemistry*
Substances
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Antineoplastic Agents
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Limonins