Abstract
Our hospital (Shanghai Skin Diseases & STD Hospital) started to study 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) in 1996. So far, we have treated 76 cases of skin cancer and pre-cancer using topical ALA-PDT. They included squamous cell carcinoma (SCC), basal cell carcinoma (BCC), Bowen's disease (BD), mammary and extramammary Paget disease, actinic keratosis (AK) and erythroplasia of Queyrat. In this overview article, we would like to present several representative cases and discuss our experience.
MeSH terms
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Administration, Topical
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Adult
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Aged
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Aminolevulinic Acid / administration & dosage
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Aminolevulinic Acid / analogs & derivatives
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Aminolevulinic Acid / therapeutic use
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Carcinoma, Basal Cell / drug therapy*
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Carcinoma, Squamous Cell / drug therapy*
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Erythroplasia / drug therapy
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Female
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Hospitalization
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Humans
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Keratosis, Actinic / drug therapy
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Male
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Middle Aged
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Paget Disease, Extramammary / drug therapy*
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Photochemotherapy*
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Precancerous Conditions* / drug therapy
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Skin Neoplasms / drug therapy*
Substances
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2-amino-5-hydroxy-4-oxopentanoic acid
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Aminolevulinic Acid