Therapeutic drug monitoring of clozapine in a hemodialysed smoking patient with schizophrenia

Ther Drug Monit. 2009 Jun;31(3):281-2. doi: 10.1097/FTD.0b013e3181a1c856.

Abstract

We describe a 38-year-old smoking woman suffering from schizophrenia, hemodialysed 3 times a week, and treated with clozapine. Therapeutic drug monitoring of clozapine was performed to guide therapy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Adverse Drug Reaction Reporting Systems*
  • Clozapine / pharmacokinetics*
  • Clozapine / therapeutic use
  • Drug Interactions
  • Drug Monitoring*
  • Female
  • Humans
  • Renal Dialysis*
  • Schizophrenia / drug therapy
  • Schizophrenia / metabolism*
  • Smoking / metabolism*
  • Smoking / therapy

Substances

  • Clozapine