Relapse with malignant transformation after chemotherapy for primary mediastinal seminoma: case report

Satoru Iwasa; Masashi Ando; Makiko Ono; Taizo Hirata; Mayu Yunokawa; Eriko Nakano; Kan Yonemori; Tsutomu Kouno; Chikako Shimizu; Kenji Tamura; Noriyuki Katsumata; Yasuhiro Fujiwara

doi:10.1093/jjco/hyp034

Relapse with malignant transformation after chemotherapy for primary mediastinal seminoma: case report

Jpn J Clin Oncol. 2009 Jul;39(7):456-9. doi: 10.1093/jjco/hyp034. Epub 2009 Apr 24.

Authors

Satoru Iwasa¹, Masashi Ando, Makiko Ono, Taizo Hirata, Mayu Yunokawa, Eriko Nakano, Kan Yonemori, Tsutomu Kouno, Chikako Shimizu, Kenji Tamura, Noriyuki Katsumata, Yasuhiro Fujiwara

Affiliation

¹ Division of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.

PMID: 19395465
DOI: 10.1093/jjco/hyp034

Abstract

This case report details a relapse with malignant transformation after the completion of bleomycin, etoposide and cisplatin chemotherapy for primary mediastinal seminoma, although the residual mass after chemotherapy was <3 cm in size and did not display an increased uptake of fluorodeoxyglucose when examined using positron emission tomography.

Publication types

Case Reports

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Biomarkers, Tumor / analysis
Bleomycin / administration & dosage
Cisplatin / administration & dosage
Etoposide / administration & dosage
Fluorodeoxyglucose F18
Humans
Male
Mediastinal Neoplasms / chemistry
Mediastinal Neoplasms / drug therapy*
Mediastinal Neoplasms / pathology
Neoplasm Recurrence, Local / chemistry
Neoplasm Recurrence, Local / diagnosis
Neoplasm Recurrence, Local / etiology*
Positron-Emission Tomography
Radiopharmaceuticals
Seminoma / chemistry
Seminoma / drug therapy*
Seminoma / pathology
Tomography, X-Ray Computed
Treatment Outcome

Substances

Biomarkers, Tumor
Radiopharmaceuticals
Fluorodeoxyglucose F18
Bleomycin
Etoposide
Cisplatin