This self-directed learning module highlights select spine and neurological injuries in athletes and performing arts injuries. It is part of the study guide on sports and performing arts medicine in the Self-Directed Physiatric Education Program for practitioners and trainees in physical medicine and rehabilitation. Using a case vignette format, this article specifically focuses on sports-induced concussion, stingers and transient myelopathy, and buttock pain in athletes, and hand dystonia and hand numbness in musicians. The goal of this article is to facilitate the learner's ability to diagnose and treat spine and neurologic injuries in athletes and performing artists.