Transplantation of endothelium and descemet membrane for aphakic corneal edema in 1980

J Refract Surg. 2010 Jul;26(7):525-8. doi: 10.3928/1081597X-20090910-01.

Abstract

Purpose: To describe a corneal endothelial layer and Descemet membrane transplantation into the anterior chamber for the treatment of bullous keratopathy in 1980.

Methods: A retrospective report of an intervention case study is presented. A patient with aphakic bullous keratopathy in one eye was interested in undergoing a previously untested corneal transplantation procedure. Snellen visual acuity testing and slit-lamp examination were performed. The main outcome measures were visual acuity and degree of corneal clarity.

Results: Visual acuity and corneal clarity improved in the months following the endothelial/Descemet membrane transplant but gradually returned to preoperative levels 1 year later. A subsequent successful penetrating keratoplasty resulted in excellent visual acuity (-20/25).

Conclusions: An attempt to perform endothelial and Descemet membrane transplantation for aphakic corneal edema in 1980 resulted in early improvement in corneal clarity and visual acuity but required full penetrating keratoplasty at 2 years postoperatively. [J Refract Surg. 2010;26(7):525-528.] doi:10.3928/1081597X-20090910-01

MeSH terms

  • Aphakia, Postcataract / physiopathology
  • Aphakia, Postcataract / surgery*
  • Cornea / physiopathology
  • Corneal Edema / physiopathology
  • Corneal Edema / surgery*
  • Descemet Membrane*
  • Endothelium, Corneal / transplantation*
  • Humans
  • Keratoplasty, Penetrating
  • Refraction, Ocular / physiology
  • Retrospective Studies
  • Suture Techniques
  • Tissue Donors
  • Visual Acuity / physiology