Abstract
The course of the disease in a patient with multiple endocrine neoplasia type IIa over a period of seven years is described. In spite of multiple diagnostic procedures, only a bone marrow biopsy was able to prove metastatic disease. All therapeutic measures, such as combination chemotherapy, sandostatin, bromocriptine, and 131Iodinemethylendiphosphonate-therapy were not effective in reducing tumor load or symptoms.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Biomarkers, Tumor / blood
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Biopsy, Needle
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Bone Marrow / pathology*
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Calcitonin / blood
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Carcinoembryonic Antigen / blood
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Carcinoma / diagnosis
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Carcinoma / therapy*
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Combined Modality Therapy
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Follow-Up Studies
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Humans
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Male
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Multiple Endocrine Neoplasia / diagnosis
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Multiple Endocrine Neoplasia / therapy*
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Thyroid Neoplasms / diagnosis
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Thyroid Neoplasms / therapy*
Substances
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Biomarkers, Tumor
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Carcinoembryonic Antigen
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Calcitonin