Postexcisional breast magnetic resonance imaging in patients with breast cancer: predictable findings of residual cancer

J Comput Assist Tomogr. 2009 Nov-Dec;33(6):940-5. doi: 10.1097/RCT.0b013e3181a6b719.

Abstract

Objective: The purposes of this study were to present magnetic resonance imaging (MRI) findings in patients with breast cancer soon after the excisional biopsy and before definitive surgery and to assess the diagnostic accuracy of MRI for prediction of residual cancer.

Methods: Breast MRI was performed on 51 patients with breast cancer diagnosed by excisional biopsy. The morphologic type of postexcisional site was categorized into regular thin rim enhancement (P1), peripheral nodular enhancement (P2), satellite nodule within 2 mm from the cavity margin (P3), and irregularly thickened wall enhancement (P4). Enhancement pattern was categorized into "washout," "plateau," and "progressive" enhancement. All patients underwent definitive surgery after MRI. Magnetic resonance imaging findings were correlated with the pathologic findings.

Results: The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of MRI for prediction of residual cancer were 92.1%, 69.2%, 78.4%, 88.6%, 56.3%, respectively.

Conclusion: MRI is a sensitive method for prediction of residual cancer after excisional biopsy.

MeSH terms

  • Adult
  • Aged
  • Biopsy*
  • Breast Neoplasms / pathology*
  • Breast Neoplasms / surgery
  • Contrast Media
  • Female
  • Gadolinium DTPA
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Middle Aged
  • Neoplasm, Residual / diagnosis*
  • Predictive Value of Tests
  • Sensitivity and Specificity

Substances

  • Contrast Media
  • Gadolinium DTPA