Molecular diversity of spider venom

Biochemistry (Mosc). 2009 Dec;74(13):1505-34. doi: 10.1134/s0006297909130069.

Abstract

Spider venom, a factor that has played a decisive role in the evolution of one of the most successful groups of living organisms, is reviewed. Unique molecular diversity of venom components including substances of variable structure (from simple low molecular weight compounds to large multidomain proteins) with different functions is considered. Special attention is given to the structure, properties, and biosynthesis of toxins of polypeptide nature.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Biological Evolution
  • Disulfides / chemistry
  • Humans
  • Insect Proteins / chemistry*
  • Insect Proteins / genetics
  • Insect Proteins / metabolism*
  • Models, Molecular
  • Molecular Sequence Data
  • Molecular Structure
  • Molecular Weight
  • Peptides / chemistry
  • Peptides / genetics
  • Peptides / metabolism
  • Protein Structure, Tertiary
  • Sequence Alignment
  • Spider Venoms / chemistry*
  • Spider Venoms / genetics
  • Spider Venoms / metabolism*
  • Spiders

Substances

  • Disulfides
  • Insect Proteins
  • Peptides
  • Spider Venoms