The value of different magnetic resonance imaging sequences for the detection of intraventricular hemorrhages*

Clin Neuroradiol. 2010 Mar;20(1):38-47. doi: 10.1007/s00062-010-0026-5. Epub 2010 Feb 28.

Abstract

Purpose: The aim of this study was to determine the value of different magnetic resonance imaging (MRI) sequences for the diagnosis of intraventricular hemorrhages (IVHs).

Patients and methods: The study included 22 consecutive patients with computed tomography (CT) proven IVH in which an MR examination had been performed. Proton-density-(PD-), T2-, fluid-attenuated inversion-recovery (FLAIR), T1- and T2*-weighted images were evaluated retrospectively by two neuroradiologists regarding presence and anatomical distribution of IVH, and cerebrospinal fluid (CSF) flow artifacts. CT was used as gold standard.

Results: According to CT, IVH was located in the right/left lateral ventricles in 16/17 patients, in the third ventricle in seven and in the fourth ventricle in twelve cases. PD- and T2*-weighted images both showed a 100% sensitivity and specificity for the overall diagnosis of IVH, and a high sensitivity for the detection of IVH in all four ventricles. The sensitivity of T1-, T2- and FLAIR- weighted images for the overall presence of an IVH was 77%, 85%, and 93%, respectively, with specificities of 100%. CSF flow artifacts occurred predominantly in the third and fourth ventricles. While FLAIR- and T2-weighted sequences were especially prone to this phenomenon, T1-, T2*- and PD-weighted images showed a higher resistance to those artifacts.

Conclusion: This study demonstrates a high sensitivity of PD- and T2*-weighted images in the detection of IVH. On the contrary, T2-, T1- and FLAIR-weighted sequences were not suitable for a reliable detection of IVH.

MeSH terms

  • Adult
  • Aged
  • Cerebral Hemorrhage / pathology*
  • Cerebral Ventricles / pathology*
  • Female
  • Humans
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods*
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed / methods*