Identification of HLA-DPA1*020107 in an individual of Ugandan descent

Chris Czarnecki; Ma Luo; Robert Brunham; Kristina Broliden; Annika C Karlsson; Francis A Plummer

doi:10.1016/j.humimm.2010.05.003

Identification of HLA-DPA1*020107 in an individual of Ugandan descent

Hum Immunol. 2010 Jul;71(7):733-5. doi: 10.1016/j.humimm.2010.05.003. Epub 2010 May 12.

Authors

Chris Czarnecki¹, Ma Luo, Robert Brunham, Kristina Broliden, Annika C Karlsson, Francis A Plummer

Affiliation

¹ National Microbiology Laboratory, Winnipeg, Manitoba, Canada.

PMID: 20470845
DOI: 10.1016/j.humimm.2010.05.003

Abstract

DPA1*020107 was identified from a woman of Ugandan origin by a taxonomy-based sequence analysis of human leukocyte antigen DPA1. The new allele was confirmed by cloning and sequencing of the polymerase chain reaction products. It is identical to DPA1*020101 with the exception of a single nucleotide synonymous substitution at codon 58 (GGC-->GGT). The World Health Organization Nomenclature Committee has named the allele as DPA1*020107.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Base Sequence / genetics
Black People
Cloning, Molecular
Female
Genotype
HLA Antigens / genetics
HLA-DP Antigens / genetics*
HLA-DP alpha-Chains
Humans
Molecular Sequence Data
Point Mutation / genetics
Polymerase Chain Reaction
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid
Uganda

Substances

HLA Antigens
HLA-DP Antigens
HLA-DP alpha-Chains
HLA-DPA1 antigen

Associated data

GENBANK/GQ374477