The authors analysed 725 clinical observations over patients who underwent combined operations for gastric carcinoma. The immediate and late-term results of these interventions were studied. Improvement of the operative techniques and the methods of pre- and postoperative management of the patients led to a decrease of the mortality to 12.3%. Five-year survival after combined operations in gastric carcinoma was 17.9 +/- 1.8%. The authors recommend specific drug therapy as an adjuvant measure in combined interventions in patients with endophytic and mixed forms of growth and metastases in the regional lymph nodes.