Abstract
We describe an exceptional case of Candida tropicalis sepsis in a patient submitted to allogeneic BMT; the diagnosis was made on a peripheral blood smear, when the pt was neutropenic and only mildly febrile. The combination of GM-CSF to accelerate hematological recovery and the possibility of administering large doses of a liposomal form of Amphotericin B were the contributing factors to the resolution of the infection.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Agranulocytosis / etiology
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Amphotericin B / administration & dosage
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Amphotericin B / therapeutic use
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Bone Marrow Transplantation / adverse effects*
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Candidiasis / drug therapy
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Candidiasis / etiology*
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Catheterization, Central Venous / adverse effects
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Combined Modality Therapy
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Drug Carriers
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Graft vs Host Disease / complications
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Humans
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Immunologic Factors / therapeutic use
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Immunosuppressive Agents / adverse effects
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Interferon Type I / therapeutic use
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive / surgery*
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive / therapy
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Liposomes
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Male
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Otitis Externa / etiology
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Pseudomonas Infections / etiology
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Recombinant Proteins
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Sepsis / drug therapy
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Sepsis / etiology*
Substances
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Drug Carriers
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Immunologic Factors
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Immunosuppressive Agents
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Interferon Type I
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Liposomes
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Recombinant Proteins
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Amphotericin B