Serogroup A Neisseria meningitidis of clone III-1 present in western Norway as early as 1969-73

Scand J Infect Dis. 1990;22(2):241-2. doi: 10.3109/00365549009037910.

Abstract

A clone of serogroup A Neisseria meningitidis recognized by multilocus enzyme electrophoresis and designated as clone III-1, has caused major epidemics of meningococcal disease in various parts of the world since the 1970s. In Norway, serogroup B meningococci have been responsible for an epidemic since the mid-1970s. We have studied a sample of 53 meningococci isolated from patients in western Norway prior to the serogroup B epidemic. 22/35 meningococcal isolates collected 1969-73 represented clone III-1, whereas this clone was not found in the 18 isolates from 1962-68. It has been speculated that the epidemic of meningococcal disease in Finland caused by clone III-1 in 1973-75 had spread from an epidemic in USSR that began in 1969. Our findings demonstrate, however, that the clone III-1 was present in Scandinavia in 1969.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Clone Cells
  • Disease Outbreaks*
  • Humans
  • Meningitis, Meningococcal / epidemiology*
  • Meningitis, Meningococcal / microbiology
  • Neisseria meningitidis / classification*
  • Neisseria meningitidis / isolation & purification
  • Norway / epidemiology
  • Serotyping
  • Time Factors