An analysis of inflation times during balloon-assisted aneurysm coil embolization and ischemic complications

Stroke. 2011 Apr;42(4):1051-5. doi: 10.1161/STROKEAHA.110.602276. Epub 2011 Feb 10.

Abstract

Background and purpose: The introduction of balloon remodeling has revolutionized the approach to coiling of wide-neck aneurysms. We studied the effects of balloon inflation during coil embolization on ischemic complications.

Methods: A retrospective review was undertaken of the most recent 147 patients undergoing balloon remodeling for unruptured intracranial aneurysm coil embolization at a single institution (81 balloon, 66 unassisted). All underwent postprocedural MRI.

Results: Among patients in the "balloon" group, the mean total inflation time was 18 minutes (range, 1-43), a mean number of inflations of 4 (range, 1-9), a mean maximum single inflation time of 7 minutes (range, 1-19), a mean reperfusion time of 2.2 minutes between inflations, and an average procedure time of 2 hours and 10 minutes. Asymptomatic diffusion-weighted imaging abnormalities were detected on postprocedural MRI in 21.5% of patients and symptomatic lesions were identified in 3.8%. Both silent and symptomatic ischemic rates were similar in the internal control group. Patients with ischemic findings were older and more likely have diabetes; no differences were found with respect to total balloon inflation time, number of inflations, maximum inflation time, or reperfusion times.

Conclusions: We found no significant relationship between balloon inflation practices and ischemic events. Older and diabetic patients were more likely to have ischemic events develop.

MeSH terms

  • Aged
  • Balloon Occlusion / adverse effects*
  • Balloon Occlusion / instrumentation
  • Balloon Occlusion / methods
  • Blood Vessel Prosthesis Implantation / adverse effects*
  • Blood Vessel Prosthesis Implantation / instrumentation
  • Blood Vessel Prosthesis Implantation / methods
  • Brain Ischemia / epidemiology*
  • Brain Ischemia / prevention & control
  • Cerebral Arteries / pathology
  • Comorbidity
  • Diffusion Magnetic Resonance Imaging / methods
  • Female
  • Humans
  • Intracranial Aneurysm / complications
  • Intracranial Aneurysm / diagnosis
  • Intracranial Aneurysm / therapy*
  • Male
  • Middle Aged
  • Postoperative Complications / etiology*
  • Postoperative Complications / prevention & control
  • Retrospective Studies
  • Risk Factors
  • Time Factors