No efficacy of prednisolone in acute wheezing associated with human bocavirus infection

Pediatr Infect Dis J. 2011 Jun;30(6):521-3. doi: 10.1097/INF.0b013e318216dd81.

Abstract

The efficacy of prednisolone in acute wheezing associated with human bocavirus infection was investigated in 232 hospitalized children (median age, 1.6 years). Clinical history, atopy status, and viral etiology were carefully studied. Outcomes included hospitalization time, duration of symptoms, and occurrence of relapses. No efficacy of prednisolone was found in children with serologically confirmed acute human bocavirus infection.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage*
  • Child
  • Child, Preschool
  • Female
  • Human bocavirus / isolation & purification*
  • Human bocavirus / pathogenicity
  • Humans
  • Infant
  • Length of Stay / statistics & numerical data
  • Male
  • Parvoviridae Infections / complications*
  • Parvoviridae Infections / drug therapy*
  • Parvoviridae Infections / pathology
  • Parvoviridae Infections / virology
  • Prednisolone / administration & dosage*
  • Recurrence
  • Respiratory Sounds / drug effects*
  • Respiratory Sounds / physiopathology
  • Treatment Outcome

Substances

  • Anti-Inflammatory Agents
  • Prednisolone