Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning

Cell Res. 2011 Jun;21(6):979-82. doi: 10.1038/cr.2011.70. Epub 2011 Apr 19.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cell Nucleus / genetics*
  • Cloning, Molecular / methods*
  • Deoxyribonucleases / chemistry
  • Deoxyribonucleases / genetics
  • Gene Knockout Techniques / methods*
  • HeLa Cells
  • Heterozygote
  • Humans
  • Molecular Sequence Data
  • Mutagenesis, Insertional
  • PPAR gamma / genetics*
  • Swine / genetics*
  • Zinc Fingers*

Substances

  • PPAR gamma
  • Deoxyribonucleases