Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia

Leukemia. 2011 Oct;25(10):1649-52. doi: 10.1038/leu.2011.134. Epub 2011 May 31.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 5-Methylcytosine / analogs & derivatives
  • Cytosine / analogs & derivatives*
  • Cytosine / metabolism
  • DNA-Binding Proteins / genetics*
  • Dioxygenases
  • Gene Expression Profiling*
  • Humans
  • In Situ Hybridization, Fluorescence
  • Leukemia, Myeloid, Acute / metabolism*
  • Mutation*
  • Proto-Oncogene Proteins / genetics*

Substances

  • DNA-Binding Proteins
  • Proto-Oncogene Proteins
  • 5-hydroxymethylcytosine
  • 5-Methylcytosine
  • Cytosine
  • Dioxygenases
  • TET2 protein, human