Sequencing of a single HLA-B genotype including two rare alleles allows the detection of a new allele, B*44:130

Tissue Antigens. 2011 Nov;78(5):398-9. doi: 10.1111/j.1399-0039.2011.01723.x. Epub 2011 Jun 27.

Abstract

The novel HLA-B*44:130 allele was found in a Spanish donor. B*44:130 differs from B*44:40 by four nucleotide changes at codons 11, 12 and 24, producing three amino acid replacements, 11A>S, 12M>V and 24T>S.

MeSH terms

  • Alleles
  • Base Sequence
  • Codon
  • Genotype
  • HLA-B Antigens / genetics*
  • Humans
  • Molecular Sequence Data
  • White People

Substances

  • Codon
  • HLA-B Antigens