Evaluation of three automated systems for susceptibility testing of enterobacteria containing qnrB, qnrS, and/or aac(6')-Ib-cr

J Clin Microbiol. 2011 Sep;49(9):3343-5. doi: 10.1128/JCM.00563-11. Epub 2011 Jul 20.

Abstract

The accuracy of the MicroScan WalkAway, BD Phoenix, and Vitek-2 systems for susceptibility testing of quinolones and aminoglycosides against 68 enterobacteria containing qnrB, qnrS, and/or aac(6 ')-Ib-cr was evaluated using reference microdilution. Overall, one very major error (0.09%), 6 major errors (0.52%), and 45 minor errors (3.89%) were noted.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminoglycosides / pharmacology
  • Anti-Bacterial Agents / pharmacology*
  • Automation / methods*
  • Diagnostic Errors / statistics & numerical data
  • Enterobacteriaceae / drug effects*
  • Genes, Bacterial
  • Humans
  • Microbial Sensitivity Tests / methods
  • Quinolones / pharmacology

Substances

  • Aminoglycosides
  • Anti-Bacterial Agents
  • Quinolones