A carbohydrate modified fluoride ion sensor and its applications

Anal Chim Acta. 2011 Oct 10;703(2):219-25. doi: 10.1016/j.aca.2011.07.009. Epub 2011 Jul 27.

Abstract

A new fluorescent probe for the detection of F(-) (TBA(+) and Na(+) salts) has been developed, which is based on a desilylation triggered chromogenic reaction in water. This probe exhibits excellent F(-) ion selectivity as well as significant color changes visible to the naked eye at the concentration of 1.5 mg L(-1), the WHO recommended level of F(-) ions in drinking water. This new carbohydrate modified probe can be used directly in aqueous medium without using organic co-solvents. Furthermore, the probe presents high sensitivity and selectivity for the imaging of F(-) ions in HepG2 cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbohydrates / chemistry*
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry
  • Fluorides / chemistry*
  • Hep G2 Cells
  • Humans
  • Ions / chemistry
  • Microscopy, Confocal
  • Spectrometry, Fluorescence / methods*
  • Water / chemistry

Substances

  • Carbohydrates
  • Fluorescent Dyes
  • Ions
  • Water
  • Fluorides