3-5 BI-RADs Microcalcifications: Correlation between MRI and Histological Findings

Valeria Fiaschetti; Chiara Adriana Pistolese; Tommaso Perretta; Elsa Cossu; Chiara Arganini; Claudia Salimbeni; Angela Lia Scarano; Silvia Arduini; Giovanni Simonetti

doi:10.5402/2011/643890

3-5 BI-RADs Microcalcifications: Correlation between MRI and Histological Findings

ISRN Oncol. 2011:2011:643890. doi: 10.5402/2011/643890. Epub 2011 Aug 25.

Authors

Valeria Fiaschetti¹, Chiara Adriana Pistolese, Tommaso Perretta, Elsa Cossu, Chiara Arganini, Claudia Salimbeni, Angela Lia Scarano, Silvia Arduini, Giovanni Simonetti

Affiliation

¹ Department of Diagnostic Imaging, Molecular Imaging, Interventional Radiology and Radiotherapy, University of Tor Vergata, Viale Oxford 81, 00133 Rome, Italy.

Abstract

Purpose. To evaluate the correlation between MRI and histopathological findings in patients with mammographically detected 3-5 BI-RAD (Breast Imaging Reporting And Data Systems) microcalcifications and to allow a better surgical planning. Materials and Method. 62 female Patients (age 50 ± 12) with screening detected 3-5 BI-RAD microcalcifications underwent dynamic 3 T contrast-enhanced breast MRI. After 30-day (range 24-36 days) period, 55 Patients underwent biopsy using stereotactic vacuum-assisted biopsy (VAB), 5 Patients underwent stereotactic mammographically guided biopsy, and 2 Patients underwent MRI-guided VAB. Results. Microhistology examination demonstrated 36 malignant lesions and 26 benign lesions. The analysis of MRI findings identified 8 cases of MRI BI-RADS 5, 23 cases of MRI BI-RADS 4, 11 cases of MRI BI-RADS 3, 4 cases type A and 7 cases type B, and 20 cases of MRI BI-RADS 1-2. MRI sensitivity, specificity, positive predictive value, and negative predictive value were 88.8%, 76.9%, 84.2%, and 83.3%, respectively.