Rapid detection of FLT3 exon 20 tyrosine kinase domain mutations in patients with acute myeloid leukemia by high-resolution melting analysis

Leuk Lymphoma. 2012 Jun;53(6):1225-9. doi: 10.3109/10428194.2011.645817. Epub 2012 Jan 13.
No abstract available

Publication types

  • Evaluation Study
  • Letter
  • Validation Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Catalytic Domain / genetics
  • DNA Mutational Analysis / methods*
  • Exons / genetics
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Leukemia, Myeloid, Acute / diagnosis
  • Leukemia, Myeloid, Acute / genetics*
  • Male
  • Middle Aged
  • Mutation* / physiology
  • Nucleic Acid Denaturation / genetics
  • Protein-Tyrosine Kinases / chemistry
  • Protein-Tyrosine Kinases / genetics
  • Time Factors
  • fms-Like Tyrosine Kinase 3 / analysis
  • fms-Like Tyrosine Kinase 3 / chemistry
  • fms-Like Tyrosine Kinase 3 / genetics*

Substances

  • FLT3 protein, human
  • Protein-Tyrosine Kinases
  • fms-Like Tyrosine Kinase 3