Synthesis of superparamagnetic Fe3O4/PMMA/SiO2 nanorattles with periodic mesoporous shell for lysozyme adsorption

Nanoscale. 2012 Apr 7;4(7):2264-7. doi: 10.1039/c2nr12125e. Epub 2012 Mar 2.

Abstract

A new kind of nanorattle, composed of a Fe(3)O(4)/polymethyl methacrylate (PMMA) composite nanospherical core and mesoporous SiO(2) shell, has been successfully synthesized with the combination of a modified stöber method and a dual-template strategy, followed by alcohol dialysis. The nanorattles showed high efficiency in protein adsorption and separation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adsorption
  • Drug Carriers / chemical synthesis
  • Drug Carriers / chemistry
  • Ferrosoferric Oxide / chemical synthesis
  • Ferrosoferric Oxide / chemistry*
  • Magnetics / methods
  • Metal Nanoparticles / chemistry*
  • Microspheres
  • Models, Biological
  • Muramidase / pharmacokinetics*
  • Polymethyl Methacrylate / chemical synthesis
  • Polymethyl Methacrylate / chemistry*
  • Porosity
  • Silicon Dioxide / chemical synthesis
  • Silicon Dioxide / chemistry*
  • Spectrum Analysis

Substances

  • Drug Carriers
  • Silicon Dioxide
  • Polymethyl Methacrylate
  • Muramidase
  • Ferrosoferric Oxide