NLRX1 has a tail to tell

Tsan Sam Xiao; Jenny P-Y Ting

doi:10.1016/j.immuni.2012.03.002

NLRX1 has a tail to tell

Immunity. 2012 Mar 23;36(3):311-2. doi: 10.1016/j.immuni.2012.03.002.

Authors

Tsan Sam Xiao¹, Jenny P-Y Ting

Affiliation

¹ Structural Immunobiology Unit, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. [email protected]

Abstract

In this issue of Immunity, Hong et al. (2012) report the first structural analysis of the C-terminal fragment of an NLR (nucleotide-binding domain [NBD] and leucine-rich repeat [LRR]-containing) protein, NLRX1. This fragment forms a hexamer and binds RNA.

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