A case of spontaneous intracranial hypotension: from Ménière-like syndrome to cerebral involvement

Eur Ann Otorhinolaryngol Head Neck Dis. 2012 Jun;129(3):153-6. doi: 10.1016/j.anorl.2011.08.005. Epub 2012 Mar 23.

Abstract

Introduction: Spontaneous intracranial hypotension (SIH) is a rare pathology caused by unexplained and variably localized leakage of cerebrospinal fluid (CSF). The prime symptom is orthostatic headache, although other less specific clinical signs may predominate, and mislead diagnosis.

Case report: A 47-year-old man presented with Ménière-like symptoms of sudden onset. Secondary orthostatic headache led to the performance of cerebral MRI, which found signs suggestive of intracranial hypotension. A blood-patch was immediately carried out, and was followed by consciousness disorder associated with onset of bilateral subdural hematoma, which required iterative neurosurgical drainage. Myelo-CT confirmed CSF leakage facing the right 12th dorsal nerve root sheath. Radio-guided sealing with biologic glue provided complete regression of all symptoms.

Discussion/conclusion: Auditory signs may predominate in the clinical presentation of SIH. Their orthostatic character is suggestive. The present case is of a rare severe form. The role of neurosurgery in such cases remains to be defined.

Publication types

  • Case Reports

MeSH terms

  • Audiometry, Pure-Tone
  • Blood Patch, Epidural
  • Cerebrospinal Fluid / physiology*
  • Diagnosis, Differential
  • Drainage
  • Fibrin Tissue Adhesive / administration & dosage
  • Hematoma, Subdural / diagnosis
  • Hematoma, Subdural / physiopathology
  • Hematoma, Subdural / therapy
  • Humans
  • Intracranial Hypotension / diagnosis*
  • Intracranial Hypotension / physiopathology*
  • Intracranial Hypotension / therapy
  • Lumbar Vertebrae
  • Magnetic Resonance Imaging
  • Male
  • Meniere Disease / diagnosis*
  • Meniere Disease / physiopathology*
  • Meniere Disease / therapy
  • Middle Aged
  • Myelography
  • Spinal Nerve Roots / physiopathology
  • Tissue Adhesives / administration & dosage
  • Tomography, X-Ray Computed

Substances

  • Fibrin Tissue Adhesive
  • Tissue Adhesives