[Cerebrovascular accident with haemorrhagic transformation in a patient on antiplatelet treatment subjected to surgery of a hypophyseal macroadenoma]

Rev Esp Anestesiol Reanim. 2012 Oct;59(8):448-51. doi: 10.1016/j.redar.2012.06.003. Epub 2012 Jul 17.
[Article in Spanish]

Abstract

The case is presented of a 51 year-old woman, proposed for endoscopic endonasal transsphenoidal resection of a hypophyseal macroadenoma diagnosed in the context of a stroke suffered 10 weeks before the date of the surgery. During this time, she had been treated with antiplatelet drugs, which were withdrawn 5 days before the surgery. The surgical procedure was performed without any incidents. On the second day after the surgery, the patient had an ischaemic infarction of the left cerebellar hemisphere, with signs of hydrocephaly and a posterior haemorrhagic transformation, with brain death 5 days after the operation. There are no definitive guidelines on the use of antiplatelet drugs in the perioperative period of neurosurgery. Also, there is no agreement as regards the waiting time between a cerebrovascular event and surgery, it appears that between 4 and 12 weeks would be the most advisable. The importance of an individual assessment of each patient before surgery is emphasised, as well as a review of the antiplatelet management of the patient with a risk of thrombosis in the context of neurosurgery, and their possible postoperative complications.

Publication types

  • Case Reports

MeSH terms

  • Adenoma / complications
  • Adenoma / diagnostic imaging
  • Adenoma / surgery*
  • Aphasia, Broca / diagnostic imaging
  • Aphasia, Broca / etiology
  • Aspirin / administration & dosage
  • Aspirin / adverse effects*
  • Aspirin / therapeutic use
  • Cerebellum / blood supply
  • Cerebral Hemorrhage / chemically induced
  • Cerebral Hemorrhage / etiology*
  • Cerebral Hemorrhage / surgery
  • Craniotomy
  • Disease Progression
  • Drainage
  • Endoscopy*
  • Fatal Outcome
  • Female
  • Growth Hormone-Secreting Pituitary Adenoma / complications
  • Growth Hormone-Secreting Pituitary Adenoma / diagnostic imaging
  • Growth Hormone-Secreting Pituitary Adenoma / surgery*
  • Hematoma / chemically induced
  • Hematoma / etiology
  • Hematoma / surgery
  • Humans
  • Hypophysectomy*
  • Intracranial Hypertension / etiology
  • Intracranial Hypertension / surgery
  • Ischemic Attack, Transient / diagnostic imaging
  • Ischemic Attack, Transient / etiology
  • Middle Aged
  • Pituitary Neoplasms / complications
  • Pituitary Neoplasms / diagnostic imaging
  • Pituitary Neoplasms / surgery*
  • Platelet Aggregation Inhibitors / administration & dosage
  • Platelet Aggregation Inhibitors / adverse effects*
  • Platelet Aggregation Inhibitors / therapeutic use
  • Postoperative Hemorrhage / chemically induced
  • Postoperative Hemorrhage / etiology*
  • Postoperative Hemorrhage / surgery
  • Radiography
  • Vertebrobasilar Insufficiency / etiology

Substances

  • Platelet Aggregation Inhibitors
  • Aspirin