Currently, single cell oils (SCO) attract much attention because of their bi-function as a supplier of functional oils and feedstock for biodiesel production. However, high fermentation costs prevent their further application, and the possibility and potential of their industrialization is suspected. Therefore, various low-cost, hydrophilic and hydrophobic substrates were utilized for SCO production. Of these substrates, lignocellulosic biomass, which is the most available and renewable source in nature, might be an ideal raw material for SCO production. Although many reviews on SCO have been published, few have focused on SCO production from low-cost substrates or evaluated the possibility and potential of its industrialization. Therefore, this review mainly presents information on SCO and its production using low-cost substrates and mostly focuses on lignocellulosic biomass. Finally, the possibility and potential of SCO industrialization is evaluated.
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