Metastatic papillary thyroid cancer with lateral neck disease: pattern of spread by level

Head Neck. 2013 Oct;35(10):1439-42. doi: 10.1002/hed.23149. Epub 2012 Sep 10.

Abstract

Background: Currently, there is no clear consensus on the extent of this lateral neck dissection required in papillary thyroid cancer (PTC) with lateral neck metastasis. The purpose of this study was to review our experience with metastatic PTC, and identify the pattern of lymphatic spread to the lateral neck.

Methods: A retrospective medical chart review of PTC patients treated with lateral neck dissection (levels II-Vb) at our institution between January 2004 and 2011. A total of 185 patients underwent 248 selective lateral neck dissections.

Results: Levels II, III, IV, and Vb were respectively involved in 49.3%, 76.6%, 61.6%, and 29.2% of cases.

Conclusion: We advocate for a routine excision of levels II, III, IV, and Vb in PTC with metastasize to any lateral neck level. Although we have routinely dissected level IIb, it may be appropriate to omit its dissection, as well as level Va, when there are no clinical, radiologic, or intraoperative evidence of disease involving these sublevels.

Keywords: lateral; level; metastasis; neck dissection; papillary cancer; thyroid.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Biopsy, Needle
  • Carcinoma / mortality
  • Carcinoma / pathology
  • Carcinoma / secondary*
  • Carcinoma / surgery*
  • Carcinoma, Papillary
  • Cohort Studies
  • Disease-Free Survival
  • Female
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Lymph Nodes / pathology*
  • Lymph Nodes / surgery
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Neck / surgery
  • Neck Dissection / methods
  • Neck Dissection / mortality
  • Neoplasm Invasiveness / pathology
  • Neoplasm Recurrence, Local / mortality
  • Neoplasm Recurrence, Local / pathology*
  • Neoplasm Recurrence, Local / therapy
  • Neoplasm Staging
  • Ontario
  • Retrospective Studies
  • Risk Assessment
  • Survival Analysis
  • Thyroid Cancer, Papillary
  • Thyroid Neoplasms / mortality
  • Thyroid Neoplasms / pathology*
  • Thyroid Neoplasms / secondary
  • Thyroid Neoplasms / surgery*
  • Thyroidectomy / methods*
  • Thyroidectomy / mortality
  • Treatment Outcome