Abstract
A novel and convenient organocatalytic tandem reaction has been developed for the asymmetric assembly of saturated aldehydes (or enals), nitroolefins and isatins to produce six-membered oxa-spirooxindole backbones bearing four contiguous stereogenic centers and multiple functional groups with high stereoselectivity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aldehydes / chemistry
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Alkenes / chemistry
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Catalysis
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Cycloaddition Reaction
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Indoles / chemistry*
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Pyrans / chemical synthesis
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Pyrans / chemistry*
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Spiro Compounds / chemistry*
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Stereoisomerism
Substances
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Aldehydes
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Alkenes
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Indoles
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Pyrans
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Spiro Compounds
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indole