Dealing with illumination in visual scenes: effects of ageing and Alzheimer's disease

PLoS One. 2012;7(9):e45104. doi: 10.1371/journal.pone.0045104. Epub 2012 Sep 24.

Abstract

Various visual functions decline in ageing and even more so in patients with Alzheimer's disease (AD). Here we investigated whether the complex visual processes involved in ignoring illumination-related variability (specifically, cast shadows) in visual scenes may also be compromised. Participants searched for a discrepant target among items which appeared as posts with shadows cast by light-from-above when upright, but as angled objects when inverted. As in earlier reports, young participants gave slower responses with upright than inverted displays when the shadow-like part was dark but not white (control condition). This is consistent with visual processing mechanisms making shadows difficult to perceive, presumably to assist object recognition under varied illumination. Contrary to predictions, this interaction of "shadow" colour with item orientation was maintained in healthy older and AD groups. Thus, the processing mechanisms which assist complex light-independent object identification appear to be robust to the effects of both ageing and AD. Importantly, this means that the complexity of a function does not necessarily determine its vulnerability to age- or AD-related decline.We also report slower responses to dark than light "shadows" of either orientation in both ageing and AD, in keeping with increasing light scatter in the ageing eye. Rather curiously, AD patients showed further slowed responses to "shadows" of either colour at the bottom than the top of items as if they applied shadow-specific rules to non-shadow conditions. This suggests that in AD, shadow-processing mechanisms, while preserved, might be applied in a less selective way.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aging / physiology*
  • Alzheimer Disease / physiopathology*
  • Demography
  • Female
  • Humans
  • Lighting*
  • Male
  • Photic Stimulation
  • Task Performance and Analysis
  • Visual Perception / physiology*

Grants and funding

The research was funded by a grant awarded to Andrea Tales by The BRACE Charity (Bristol Research into Alzheimer's and Care of the Elderly). http://www.alzheimers-brace.org/. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.