Bioorthogonal copper-free click chemistry in vivo for tumor-targeted delivery of nanoparticles

Angew Chem Int Ed Engl. 2012 Nov 19;51(47):11836-40. doi: 10.1002/anie.201206703. Epub 2012 Oct 18.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Azides / administration & dosage
  • Azides / chemistry
  • Azides / metabolism
  • Cell Line, Tumor
  • Click Chemistry / methods*
  • Copper / chemistry
  • Drug Delivery Systems / methods*
  • Hexosamines / administration & dosage
  • Hexosamines / chemistry
  • Hexosamines / metabolism
  • Humans
  • Liposomes / administration & dosage
  • Liposomes / chemistry
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / metabolism*
  • Mice
  • Nanoparticles / administration & dosage*
  • Nanoparticles / chemistry*
  • Polysaccharides / chemistry
  • Polysaccharides / metabolism
  • Sialic Acids / chemistry
  • Sialic Acids / metabolism
  • Xenograft Model Antitumor Assays

Substances

  • Azides
  • Hexosamines
  • Liposomes
  • N-azidoacetylmannosamine
  • Polysaccharides
  • Sialic Acids
  • Copper