Abstract
We describe the prevalence of and risk factors for colonization with extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella species (ESBL-EK) in hospitalized patients. The prevalence of colonization with ESBL-EK was 2.6%. Colonization was associated with cirrhosis, longer duration of hospital stay prior to surveillance, and prior exposure to clindamycin or meropenem.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Aged
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Anti-Bacterial Agents / therapeutic use
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Carrier State / epidemiology*
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Carrier State / microbiology
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Case-Control Studies
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Clindamycin / therapeutic use
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Escherichia coli / enzymology*
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Female
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Gastrointestinal Tract / microbiology*
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Humans
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Klebsiella / enzymology*
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Length of Stay
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Liver Cirrhosis / epidemiology
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Male
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Meropenem
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Microbial Sensitivity Tests
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Middle Aged
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Prevalence
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Rectum / microbiology
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Risk Factors
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Thienamycins / therapeutic use
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beta-Lactam Resistance
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beta-Lactamases / biosynthesis*
Substances
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Anti-Bacterial Agents
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Thienamycins
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Clindamycin
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beta-Lactamases
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Meropenem