Incidental seminal vesicle amyloidosis observed in diagnostic prostate biopsies--are routine investigations for systemic amyloidosis warranted?

Asian J Androl. 2013 Jan;15(1):149-51. doi: 10.1038/aja.2012.125. Epub 2012 Dec 10.

Abstract

Seminal vesicle (SV) amyloidosis is a well-documented histological entity, but it is observed infrequently. Its incidence is on the rise, which is probably related to the increasing use of prostate biopsies to investigate patients with elevated serum prostate-specific antigen levels. Here, we report seven cases of incidental SV amyloidosis over a 3-year period and consider their relationship to the previously suggested aetiological factors. Based on our series, we conclude that incidental localized SV amyloidosis observed in diagnostic prostate biopsies does not warrant formal investigations for systemic amyloidosis.

MeSH terms

  • Adult
  • Aged
  • Amyloidosis / diagnosis*
  • Biopsy
  • Humans
  • Immunoglobulin Light-chain Amyloidosis
  • Incidental Findings*
  • Male
  • Middle Aged
  • Prostate / diagnostic imaging*
  • Prostate / pathology
  • Prostate-Specific Antigen
  • Prostatic Neoplasms / diagnosis
  • Seminal Vesicles / pathology*
  • Ultrasonography

Substances

  • Prostate-Specific Antigen