[A successful case of a super-elderly breast cancer patient treated with hormone therapy]

Gan To Kagaku Ryoho. 2012 Nov;39(12):2042-4.
[Article in Japanese]

Abstract

A 104-year-old female patient with a left breast mass was admitted to our hospital. Ultrasonography showed an irregular and low-echoic mass of about 2.4×2.4×1.4 cm size in the left breast EAC area. Core needle biopsy examination indicated invasive ductal carcinoma of the breast: ER (+), PR (+), and HER2 (-). An overall examination did not show a distant metastasis. We diagnosed her with left breast cancer(luminal A type) T2N0M0, stage IIA. We administered anastrozole at a dose of 1 mg/day. After 6 months, the primary tumor diameter was reduced to 2.1 cm, and the effect of anastrozole was considered a clinical partial response. The patient did not experience any adverse events during treatment. The partial response was maintained for about 2 years. We experienced a successful case of a super-elderly breast cancer patient treated with anastrozole. We conclude that hormone therapy is a useful treatment for super-elderly postmenopausal women with estrogen receptor-positive breast cancer.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Anastrozole
  • Antineoplastic Agents, Hormonal / therapeutic use*
  • Biopsy, Large-Core Needle
  • Breast Neoplasms / diagnostic imaging
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / pathology
  • Carcinoma, Ductal, Breast / diagnostic imaging
  • Carcinoma, Ductal, Breast / drug therapy*
  • Carcinoma, Ductal, Breast / pathology
  • Female
  • Humans
  • Neoplasm Staging
  • Nitriles / therapeutic use*
  • Quality of Life
  • Triazoles / therapeutic use*
  • Ultrasonography

Substances

  • Antineoplastic Agents, Hormonal
  • Nitriles
  • Triazoles
  • Anastrozole