Prevalence, hematology, and treatment of balantidiasis among donkeys in and around Lahore, Pakistan

Vet Parasitol. 2013 Sep 1;196(1-2):203-5. doi: 10.1016/j.vetpar.2013.01.017. Epub 2013 Jan 30.

Abstract

The prevalence of Balantidium coli among donkeys in Lahore and adjoining areas was surveyed and a trial conducted to determine the efficacy of two antiprotozoal drugs: secnidazole (Dysen Forte) and Kalonji (Nigella sativa). Four-hundred donkeys were examined, and 73 (18.3%) were found positive for Balantidium coli. A slight decrease in PCV and an increase in Hb values of infected donkeys were found after antiprotozoal treatment. Secnidazole was 89.5% effective for the treatment of equine balantidiasis compared to 40.0% for Nigella sativa. This is the first report of balantidiasis in equines from Pakistan. It is not known if balantidiasis is an emerging problem in equines or whether it is a newly reported infection.

Keywords: Balantidium coli; Donkey; Nigella sativa; Prevalence; Secnidazole.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Animals
  • Antiprotozoal Agents / therapeutic use
  • Balantidiasis / blood
  • Balantidiasis / drug therapy
  • Balantidiasis / epidemiology
  • Balantidiasis / veterinary*
  • Equidae*
  • Female
  • Male
  • Metronidazole / analogs & derivatives*
  • Metronidazole / therapeutic use
  • Nigella sativa / chemistry*
  • Pakistan / epidemiology
  • Plant Extracts / chemistry
  • Plant Extracts / therapeutic use*
  • Prevalence

Substances

  • Antiprotozoal Agents
  • Plant Extracts
  • Metronidazole
  • secnidazole