Optimization of magnetosome production and growth by the magnetotactic vibrio Magnetovibrio blakemorei strain MV-1 through a statistics-based experimental design

Karen T Silva; Pedro E Leão; Fernanda Abreu; Jimmy A López; Melissa L Gutarra; Marcos Farina; Dennis A Bazylinski; Denise M G Freire; Ulysses Lins

doi:10.1128/AEM.03740-12

Optimization of magnetosome production and growth by the magnetotactic vibrio Magnetovibrio blakemorei strain MV-1 through a statistics-based experimental design

Appl Environ Microbiol. 2013 Apr;79(8):2823-7. doi: 10.1128/AEM.03740-12. Epub 2013 Feb 8.

Authors

Karen T Silva¹, Pedro E Leão, Fernanda Abreu, Jimmy A López, Melissa L Gutarra, Marcos Farina, Dennis A Bazylinski, Denise M G Freire, Ulysses Lins

Affiliation

¹ Universidade Federal do Rio de Janeiro, Instituto de Microbiologia Paulo de Góes, Rio de Janeiro, RJ, Brazil.

Abstract

The growth and magnetosome production of the marine magnetotactic vibrio Magnetovibrio blakemorei strain MV-1 were optimized through a statistics-based experimental factorial design. In the optimized growth medium, maximum magnetite yields of 64.3 mg/liter in batch cultures and 26 mg/liter in a bioreactor were obtained.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacterial Proteins / metabolism
Bioreactors*
Culture Media
Ferrosoferric Oxide / metabolism
Magnetic Fields
Magnetosomes / metabolism*
Research Design
Rhodospirillaceae / growth & development*
Rhodospirillaceae / metabolism*
Water Microbiology

Substances

Bacterial Proteins
Culture Media
Ferrosoferric Oxide