The presence or absence of IL-3 during long-term culture of Flt3-ITD and c-Kit-D816V expressing Ba/F3 cells influences signaling outcome

MeSH terms

• Animals
• Bone Marrow Cells / drug effects*
• Bone Marrow Cells / physiology
• Cell Division / drug effects
• Cell Line, Transformed / drug effects
• Cell Size / drug effects
• Cell Survival
• Cell Transformation, Neoplastic / genetics
• Genetic Vectors
• Humans
• Interleukin-3 / pharmacology*
• Mice
• Mutation, Missense*
• Phosphorylation / drug effects
• Point Mutation*
• Protein Processing, Post-Translational / drug effects
• Protein-Tyrosine Kinases / metabolism
• Proto-Oncogene Proteins c-kit / genetics
• Proto-Oncogene Proteins c-kit / physiology*
• Recombinant Proteins / metabolism
• Retroviridae / genetics
• STAT5 Transcription Factor / metabolism
• Signal Transduction / drug effects*
• Tandem Repeat Sequences
• Transduction, Genetic
• fms-Like Tyrosine Kinase 3 / genetics
• fms-Like Tyrosine Kinase 3 / physiology*