Biochemical heterogeneity and developmental varieties in T-cell leukemia

Cell Cycle. 2013 May 15;12(10):1480-1. doi: 10.4161/cc.24858. Epub 2013 Apr 29.
No abstract available

Keywords: CyTOF; Ras signaling; RasGRP1; T-cell leukemia; cancer; computational models; heterogeneity; kinase inhibitor; molecular therapy.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Kommentar

MeSH terms

  • Animals
  • Enzyme Activation / physiology*
  • Gene Expression Regulation, Neoplastic / physiology*
  • Guanine Nucleotide Exchange Factors / metabolism*
  • Humans
  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / metabolism*
  • Signal Transduction / physiology*
  • ras Proteins / metabolism*

Substances

  • Guanine Nucleotide Exchange Factors
  • ras Proteins