No effects of short-term sleep restriction, in a controlled feeding setting, on lipid profiles in normal-weight adults

J Sleep Res. 2013 Dec;22(6):717-20. doi: 10.1111/jsr.12060. Epub 2013 May 20.

Abstract

Short sleep has been associated with cardiovascular risk. The aim of this study was to determine the impact of short-term sleep restriction on lipid profiles and resting blood pressure factors in young, normal-weight individuals (14 men, 13 women). Participants were randomized to five nights of either habitual (9 h) or short (4 h) sleep in a cross-over design separated by a 3-week washout period. There was no sleep × day interaction on lipid profile and blood pressure. Short-term sleep restriction does not alter lipid profiles and resting blood pressure in healthy, normal-weight individuals. The association between short sleep and increased cardiovascular risk reported in the epidemiological literature may be the result of long-term sleep restriction and poor lifestyle choices.

Keywords: blood pressure; short sleep; total cholesterol; triglycerides.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Pressure / physiology
  • Body Weight*
  • Cardiovascular Diseases / blood
  • Cardiovascular Diseases / complications
  • Cardiovascular Diseases / etiology
  • Cross-Over Studies
  • Diet*
  • Female
  • Humans
  • Lipids / blood*
  • Male
  • Middle Aged
  • Risk Factors
  • Sleep / physiology
  • Sleep Deprivation / blood*
  • Sleep Deprivation / complications
  • Sleep Deprivation / metabolism*
  • Sleep Deprivation / physiopathology
  • Time Factors

Substances

  • Lipids